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Welcome to RUBICON
RUBICON is a “Network of Excellence” funded by the Framework Programme 6 of the European Commission over a five years period (January 2006 – December 2010). It is coordinated by Professor Maria Masucci, Karolinska Institutet, Stockholm, Sweden.
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News:
LA1 - The Nobel Prize for the discovery of ubiq...


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The Nobel Prize in Chemistry 2004 was awarded to Aaron Ciechanover, Avram Hershko and Irwin Rose "for the discovery of ubiquitin-mediated protein d...
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News:
LA2 - Die Happy? – Live Longer? Or how to manip...


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Agnes van Rossum, Karin Hek, Henk Vietor, and Ger Strous
UMC Utrecht in collaboration with DDF BV, Bussum, The Netherlands
A major topic in tod...
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News:
LA9 - Monoubiquitination in Endocytosis


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Raghunath Peesari and Simona Polo
IFOM, Fondazione Istituto FIRC di Oncologia Molecolare
Ubiquitin (Ub) is a 76 amino acid residue protein that...
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News:
LA3 - Pepscan Technology for Fighting Cancer
The idea that the immune system can recognize and respond to tumors was formed in the late 19th century when William Coley, a surgeon at the Memori...
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Participant:
Maria Masucci's Group
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Participant:
Thomas Sommer's Group


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The secretory pathway of eukaryotic cells harbors an elaborate protein quality control system, which prevents the accumulation of misfolded or unas...
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Participant:
DDF Research Group
DDF is involved in several drug discovery programs including finding new cures for prostate cancer, dendritic based cancer vaccines, osteoporosis a...
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Participant:
Pier Paolo Di Fiore's Group
Our lab has contributed to the characterization of two protein:protein interaction networks, the EH and the mono-ubiquitin (Ub) networks, which pla...
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Participant:
SME: Proteologics
Proteologics is a biopharmaceutical company comprising bio- and chemi-informatics, target discovery, target validation, assay development and drug...
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Participant:
CYTOMICS SYSTEMS
CYTOMICS SYSTEMS’ protein degradation approach to drug discovery relies on UbiScreen®, a patented functional screening technology relevant to all t...
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