RP - Separation of transmembrane, membrane-associated and cytosolic proteins (»Add to Infobox)

Israel Alain, Professor

Alain Israël's Group

This procedure allows separating the true transmembrane proteins(TM) from the membrane-associated proteins (MAP). For example, AIP4/Itch or members of Nedd4 family are MAPs, whereas other E3 ubiquitin ligases (like DTX) appear to be true transmembrane proteins. Non-activated Notch is a TM protein.

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Israel Alain, Professor (Principal Investigator / Alain Israël's Group)

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