Pier Paolo Di Fiore's Group - Molecular Pathology Unit (»Add to Infobox)

General description: Our goal is to identify novel putative cancer targets for drug discovery, diagnostic and/or prognostic applications. For this purpose, we use a high throughput screening technology (Tissue Microarrays, TMA) together with in situ detection methods (ISH and IHC) to rapid translate early discoveries into clinical application. Role in RUBICON: We are interested in elucidating the importance of ubiquitin and UbL post-translational modifications in basic biological processes. In particular, we aim to better clarify the implication of the subversion of this post-translational regulatory mechanism in cancer. To reach these objectives, we will use the integration of both in vitro and in vivo model systems with high-throughput screening approaches including cDNA-, oligo- and tissue- microarrays.

MEMBERS (1/1)

Nuciforo Paolo (Researcher/ Molecular Pathology Unit / Pier Paolo Di Fiore's Group)