Wednesday, 07. January 2009
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RESEARCH GROUP


Titia Sixma's Group (»Add to Infobox)


Academic: The Netherlands Cancer Institute, Amsterdam

Internet:  http://Xtal.nki.nl

General description:
Structure/function relations of proteins involved in cell cycle, transmembrane signal transduction and the maintenance of DNA-integrity studied by X-ray crystallography.

Role in RUBICON:
Structural analysis of the E2/E3/SUMO complexes and characterization of SUMO acceptor sites context. Identification, functional characterization and structural analysis of selected DUB catalytic domain complexes and development of small molecule inhibitors.


MEMBERS (6/6) 

Sixma Titia
(Principal Investigator / Titia Sixma's Group)



Patrick Celie (Crystallization facility manager / Titia Sixma's Group)

Mark Luna-Vargas (Graduate student / Titia Sixma's Group)

Rick Hibbert, Post-doc (Titia Sixma's Group)

Judith Smit, Ph.D. Student (Titia Sixma's Group)

Francesca Mattiroli, Ph.D. Student (Titia Sixma's Group)


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