Titia Sixma's Group (»Add to Infobox)

General description: Structure/function relations of proteins involved in cell cycle, transmembrane signal transduction and the maintenance of DNA-integrity studied by X-ray crystallography. Role in RUBICON: Structural analysis of the E2/E3/SUMO complexes and characterization of SUMO acceptor sites context. Identification, functional characterization and structural analysis of selected DUB catalytic domain complexes and development of small molecule inhibitors.

MEMBERS (9/9)

Sixma Titia (Principal Investigator / Titia Sixma's Group)