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C5a: 2006, May 15-19, RUBICON Course: Ubiquitin and SUMO, Stockholm, Sweden
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The first RUBICON training course "A molecular ticket to enter the cell" took place in Stockholm, Sweden, between May 15-19, 2006. The lecture course had been organised by Rubicon coordinator Maria Masucci together with Training coordinator Ger Strous and attracted 37 students, including seven Rubicon members. The course provided a survey of the role of protein-modification by the attachment of Ubiquitin or SUMO in membrane trafficking. Within the wide range of functions of ubiquitinylation and sumoylation in regulating biological processes from the plasma membrane to the nucleus, the aspect of membrane trafficking is receiving increasing attention lately.
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The lecturers are specialists at the cross-roads of membrane trafficking and ubiquitin/SUMO systems in the fields of biochemistry, molecular and cell biology and yeast genetics. In their lectures, these experts gave in-depth insights into the state-of-the-art in their fields, and presented their recent work with emphasis on novel results, the application of specific methods, troubleshooting, uses of positive and negative controls etc.
Methods applicable to study ubiquitinylation and sumoylation are relatively complicated to establish in the individual laboratory. Therefore, a detailed discussion of methodology was integrated in the presentations to teach the participating students and young researchers how to best design experiments using ubiquitinylation/sumoylation techniques.
During the course’s morning sessions the invited teachers/experts lectured for the course participants. In the early afternoon, they gave a research seminar open to the students and scientists of the Karolinska Institute, followed by lively discussions between the teachers and the audience. The course’s afternoon sessions consisted of research seminars where each of the participants presented a research paper (15 minutes and 15 minutes discussion) indicated by the teachers, again followed by open discussions. The evenings were reserved for leisure time and visits to the city of Stockholm.
Teachers
Ivan Dikic, Goethe University School of Medicine
Institute for Biochemistry II, Goethe University Medical School, Frankfurt 60590, Germany
– Course subject: Receptor endocytosis, Research lecture: Cellular signaling by protein ubiquitylation
Yosef Yarden, Department of Biological Regulation
Weizmann Institute of Science, Rehovot, Israel
– Course subject: Endocytosis adaptor proteins, Research lecture: Vesicular trafficking at the intersection of signal transduction and cancer
Benny Geiger, Department of Molecular Cell Biology
The Weizmann Institute of Science, 76100 Rehovot, Israel
– Course subject: Cell adhesion, Research lecture: Sensing the environment, mechanosensitivity of living cells
Reinhard Jahn, Department of Neurobiology
Max-Planck-Institute for Biophysical Chemistry, 37077 Gottingen, Germany
– Course subject: Vesicle fusion and trafficking, Research lecture: Research seminar by “Membrane fusion in the secretory pathway”
Wes Sundquist, Department of Biochemistry
University of Utah, Salt Lake City, UT 84132, USA
– Course subject: Virus budding, Research lecture: The biochemistry of HIV budding
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| MEMBERS (2/2) |
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Ger Strous (Principal Investigator / Ger Strous's Group)

| DOWNLOADS (1/1) |
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Course Schedule
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