Sunday, 05. February 2012

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Titia Sixma (»Add to Infobox)


Principal Investigator
Titia Sixma's Group
Academic: The Netherlands Cancer Institute, Amsterdam
Phone:  +31 20 5121959
Email:  t.sixmanki.nl

General description:
Structure and function of proteins in SUMO and ubiquitin conjugation in DNA repair and chromatin remodelling.

Link:
http://Xtal.nki.nl/titia_group



Role in RUBICON:
Structural analysis of the E2/E3/SUMO complexes and characterization of SUMO acceptor sites context. Identification, functional characterization and structural analysis of selected DUB catalytic domain complexes and development of small molecule inhibitors.


RELATED NEWS (2/2) 

C3d: 2008, May 21-23, Course on Biophysical Protein Characterization, Amsterdam, Netherlands

RP - Large-scale in vitro PCNA ubiquitinylation by Rad18/Rad6


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