RUBICON (Role of Ubiquitin and Ubiquitin-like Modifiers in Cellular Regulation) is a “Network of Excellence” funded by the Framework Programme 6 of the European Commission over a five years period (January 2006 – December 2010). It is coordinated by Professor Maria Masucci, Karolinska Institutet, Stockholm, Sweden.
The Nobel Prize in Chemistry 2004 was awarded to Aaron Ciechanover, Avram Hershko and Irwin Rose "for the discovery of ubiquitin-mediated protein d... » more
Raghunath Peesari and Simona Polo
IFOM, Fondazione Istituto FIRC di Oncologia Molecolare
Ubiquitin (Ub) is a 76 amino acid residue protein that... » more
The idea that the immune system can recognize and respond to tumors was formed in the late 19th century when William Coley, a surgeon at the Memori... » more
Modifications of the proteins play key roles in controlling protein activity and hence cell function. This is mainly due to their ability to rapidl... » more
Proteologics is a biopharmaceutical company comprising bio- and chemi-informatics, target discovery, target validation, assay development and drug... » more
The department of proteomics and signal transduction, led by Prof. Matthias Mann, was established in July 2005 and is currently comprised of 30 peo... » more
BIE R&D programs are directed towards the development of reagents and assays facilitating investigation of ubiquitin and ubiquitin-like protein (Ub... » more
The major focus of the lab is the functional identification of novel cancer-relevant genes. The completion of the sequencing of the human genome in... » more
Dieter H. Wolf’s group is concerned with intracellular regulation and protein quality control via the ubiquitin proteasome system. The yeast Saccha... » more
